Leave it ON by default for most games. It’s a harmless optimization. Only disable it if you spot pacing issues in specific titles (e.g., Shadow of the Colossus , Ratchet & Clank series).
It sounds technical, but here’s the simple breakdown: skip presenting duplicate frames pcsx2
❌ You notice weird frame pacing or micro-stutters. ❌ You’re using heavy post-processing shaders (sometimes conflicts). ❌ You’re recording/streaming and need consistent presentation timing. Leave it ON by default for most games